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GOLD-CON-05

Conflicting evidence · gold-v0.1

Case inputs

As of
2026-06-20
Patient
34 years, AZ
Request
Immunara for rheumatoid arthritis
Insurance
Northstar, Northstar Choice · NSC-224871
Policy
immunara-v0.1
Inputs
sha256:9fb02fa55a2c…

Documents 3

Physician note

problem_list
SYNTHETIC RECORD - Example Cascade Rheumatology - Problem List Update - 2026-06-08
Patient reference SYN-5502. 34-year-old woman.

- Psoriatic arthritis, asymmetric, with nail pitting and dactylitis of the third toe; rheumatoid arthritis excluded given seronegative serology and the distribution of joint involvement.
- Methotrexate 20 mg weekly from 2026-01-05 to 2026-05-18, discontinued for inadequate response.
- Mild plaque psoriasis on the scalp, stable.
- Plan: discuss Immunara given the inadequate response to methotrexate; dermatology follow-up for skin disease.

Physician note

clinic_note
SYNTHETIC RECORD - Example Cascade Rheumatology - Follow-up Visit - 2026-06-10
Patient reference SYN-5502. A second clinician at this practice saw this 34-year-old woman this week for ongoing joint symptoms.

Her chart carries an established diagnosis of rheumatoid arthritis, and her hand and wrist swelling has continued despite treatment. She completed oral methotrexate 20 mg weekly from 2026-01-05 to 2026-05-18, which was stopped because her synovitis had not improved, an inadequate response. She works as a dental hygienist and describes ongoing difficulty gripping instruments.

Immunara is recommended given her sustained disease activity.

Lab report

lab_report
SYNTHETIC RECORD - Example Cascade Rheumatology - Laboratory Report - 2026-05-28
Patient reference SYN-5502.
Rheumatoid factor: negative, 8 IU/mL (reference <14).
Anti-CCP antibody: negative, 4 U/mL (reference <20).
ESR: 30 mm/hr (elevated).
CRP: 1.6 mg/dL (elevated).

Decisions by provider

HUMAN_REVIEWcorrect

Decided by: contradiction gate · auto_process 0.89

Judgments

p_yes for yes/no questions; ticks are the thresholds a gate compares each one with.

Diagnosis supported
0.570
Step therapy met
0.960
Documentation complete
0.930
Material contradiction
0.950
Missing evidence
DIAGNOSIS 0.800
others: NONE 0.18 · DOSAGE 0.02
Gate path· 7 gates, in engine order
  1. providerpassed

    all five decisions present and well-formed

  2. agepassed

    patient.age=34, policy min_age=18

  3. contradictionFIRED → HUMAN_REVIEW

    p_yes(material_contradiction)=0.950, review at >= 0.8

  4. documentationnot reached
  5. missing_evidencenot reached
  6. auto_processnot reached
  7. default_reviewnot reached

passed = the gate checked and did not fire; not reached = an earlier gate decided.

  • a material contradiction is likely (p=0.950)
Run details· q-v0.2

run_20260925T170857Z_b95be9 · q-v0.2 · immunara-v0.1 (v0.1)

auto_process 0.89, chosen on gen-v0.2-dev.

questions: q-v0.2 →

Show expected answer (evaluation only)